*Result*: ADAPT-marketplace - A web-application for XML-based template sharing in radiation oncology.

Title:
ADAPT-marketplace - A web-application for XML-based template sharing in radiation oncology.
Authors:
Stanley DN; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Harms J; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, USA., Rathi GN; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Pogue JA; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Nedunoori R; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Fiveash JB; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Popple RA; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Cardenas CE; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Source:
Journal of applied clinical medical physics [J Appl Clin Med Phys] 2025 Jul; Vol. 26 (7), pp. e70148.
Publication Type:
Journal Article
Language:
English
Journal Info:
Publisher: Wiley on behalf of American Association of Physicists in Medicine Country of Publication: United States NLM ID: 101089176 Publication Model: Print Cited Medium: Internet ISSN: 1526-9914 (Electronic) Linking ISSN: 15269914 NLM ISO Abbreviation: J Appl Clin Med Phys Subsets: MEDLINE
Imprint Name(s):
Publication: 2017- : Malden, MA : Wiley on behalf of American Association of Physicists in Medicine
Original Publication: Reston, VA : American College of Medical Physics, c2000-
MeSH Terms:
Radiotherapy Planning, Computer-Assisted*/methods , Radiation Oncology*/methods , Neoplasms*/radiotherapy , Internet* , Programming Languages* , Software*, Radiotherapy, Intensity-Modulated/methods ; Humans ; Radiotherapy Dosage
References:
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J Appl Clin Med Phys. 2025 Jul;26(7):e70148. (PMID: 40653812)
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Grant Information:
L30CA284339 National Institutes of Health/National Cancer Institute award; UABRO2022 University of Alabama at Birmingham; 5KL2TR003097-05 United States TR NCATS NIH HHS; LRP0000018407 National Institutions of Health/National Cancer Institute
Contributed Indexing:
Keywords: XML; ethos; online adaptive radiotherapy; planning templates; radiation oncology; template repository; treatment planning
Entry Date(s):
Date Created: 20250714 Date Completed: 20250714 Latest Revision: 20250717
Update Code:
20260130
PubMed Central ID:
PMC12256657
DOI:
10.1002/acm2.70148
PMID:
40653812
Database:
MEDLINE

*Further Information*

*Purpose: The adaption of radiotherapy (RT) plans in response to anatomical and physiological changes during treatment marks a significant shift toward personalized cancer care. However, the complexity of Online Adaptive Radiotherapy (OART) procedures often leads to variability in treatment quality across institutions. The development of planning templates, particularly through the Ethos treatment planning system (TPS) and Intelligent Optimization Engine (IOE) (Varian Medical Systems, Palo Alto, CA), plays a crucial role in standardizing and streamlining OART. To address the challenges of sharing and optimizing treatment templates across diverse clinical environments, we developed the ADaptive rAdiotherapy Planning Template (ADAPT-) Marketplace to facilitate the exchange of XML-based templates and promote collaborative innovation in the OART community.
Methods: ADAPT-Marketplace was developed using the Django web framework, chosen for its security, scalability, and versatility. The platform supports the sharing of XML-based treatment planning templates, compatible with Ethos TPS, and includes features for uploading, downloading, comparing, and editing templates. The development followed a structured process, involving collaborator consultations, prototyping, and both alpha and beta testing. Testing phases included predefined tasks and unscripted evaluations, with feedback collected to refine the platform prior to its official launch.
Results: Since its launch in July 2023, ADAPT-Marketplace has registered 65 users from 16 countries and 38 institutions, including academic, non-academic and industrial sectors. Over 50 templates have been uploaded, covering treatment sites such as the pelvis, thorax, head-and-neck, and abdomen. Feedback from alpha and beta testing resulted in key improvements, including enhanced navigation, template validation, and user experience.
Conclusion: ADAPT-marketplace provides a centralized platform for sharing and collaborating on treatment planning templates, offering the potential to improve research productivity, facilitate knowledge exchange, and standardize OART practices across institutions.
(© 2025 The Author(s). Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine.)*