Treffer: Blood neurofilament light chain as a biomarker for cognitive impairment in adults with epilepsy: Integrated evidence from clinical cohorts in Northeast China and European GWAS data.

Blood neurofilament light chain as a biomarker for cognitive impairment in adults with epilepsy: Integrated evidence from clinical cohorts in Northeast China and European GWAS data.

Chen Z; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.; Human Brain and Tissue Bank, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China., Guo Y; Department of Ophthalmology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China., Yao J; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China., Lin J; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China., Sun H; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China., Li J; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China., Zhang W; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China., Hou S; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China., Meng H; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.

Epilepsia [Epilepsia] 2026 Jan; Vol. 67 (1), pp. 341-356. Date of Electronic Publication: 2025 Oct 06.

Journal Article; Observational Study

English

Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE

Publication: Malden, MA : Blackwell Science
Original Publication: Copenhagen : Munskgaard

Neurofilament Proteins*/blood , Cognitive Dysfunction*/blood , Cognitive Dysfunction*/genetics , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/diagnosis , Epilepsy*/blood , Epilepsy*/genetics , Epilepsy*/complications , Epilepsy*/psychology, Biomarkers/blood ; Humans ; Male ; Female ; Genome-Wide Association Study ; Cross-Sectional Studies ; Adult ; Middle Aged ; China ; Cohort Studies ; Mendelian Randomization Analysis ; Europe

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20240304165SF Jilin Provincial Scientific and Technological Development Program; 81801145 National Natural Science Foundation of China; 81871008 National Natural Science Foundation of China

Keywords: Mendelian randomization; biomarker; cognitive impairment; epilepsy; genome‐wide association study; neurofilament light chain

0 (Neurofilament Proteins)
0 (Biomarkers)
0 (neurofilament protein L)

Date Created: 20251006 Date Completed: 20260211 Latest Revision: 20260211

20260211

10.1111/epi.18659

41051900

MEDLINE