• Generative Artificial Intellig...

Treffer: Generative Artificial Intelligence: Applications and Future Prospects in Dentistry.

Title:
Generative Artificial Intelligence: Applications and Future Prospects in Dentistry.
Authors:
Ma Z; Department of Orthodontics, Capital Medical University School of Stomatology, Beijing, China., Du C; Department of Geriatric Dentistry, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China. Electronic address: duchenlin@hsc.pku.edu.cn., Lao Q; School of Artificial Intelligence, Beijing University of Posts and Telecommunications (BUPT), Beijing, China., Xie X; Department of Orthodontics, Capital Medical University School of Stomatology, Beijing, China. Electronic address: dentistxxj@mail.ccmu.edu.cn.
Source:
International dental journal [Int Dent J] 2026 Feb; Vol. 76 (1), pp. 108276. Date of Electronic Publication: 2025 Nov 18.
Publication Type:
Journal Article; Review
Language:
English
Journal Info:
Publisher: Elsevier Country of Publication: England NLM ID: 0374714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-595X (Electronic) Linking ISSN: 00206539 NLM ISO Abbreviation: Int Dent J Subsets: MEDLINE
Imprint Name(s):
Publication: 2021- : London : Elsevier
Original Publication: London : FDI World Dental
MeSH Terms:
Artificial Intelligence*/trends , Dentistry*/trends , Dentistry*/methods, Humans ; Forecasting ; Generative Artificial Intelligence
References:
Int J Oral Sci. 2023 Jul 28;15(1):29. (PMID: 37507396)
BMC Oral Health. 2025 Apr 28;25(1):648. (PMID: 40296000)
BMC Oral Health. 2025 Jul 28;25(1):1272. (PMID: 40721763)
Sci Data. 2024 Nov 23;11(1):1277. (PMID: 39580508)
Eur J Dent Educ. 2024 Feb;28(1):206-211. (PMID: 37550893)
BMC Oral Health. 2022 Sep 13;22(1):399. (PMID: 36100856)
IEEE Trans Med Imaging. 2024 Nov;43(11):3755-3766. (PMID: 38717880)
Nat Commun. 2025 Mar 16;16(1):2586. (PMID: 40091067)
Nat Med. 2019 Jan;25(1):30-36. (PMID: 30617336)
Nature. 2023 Aug;620(7972):172-180. (PMID: 37438534)
IEEE Trans Vis Comput Graph. 2024 Feb;30(2):1457-1469. (PMID: 36315543)
Am J Orthod Dentofacial Orthop. 2024 Jun;165(6):652-662. (PMID: 38493370)
Head Face Med. 2022 Jun 27;18(1):19. (PMID: 35761334)
J Dent Res. 2017 Apr;96(4):361-363. (PMID: 28318392)
Oral Dis. 2023 Apr;29(3):1050-1059. (PMID: 34689379)
Nature. 2023 Aug;620(7976):1089-1100. (PMID: 37433327)
J Dent Educ. 2024 Jun;88(6):872-876. (PMID: 38356365)
BMC Oral Health. 2024 May 24;24(1):605. (PMID: 38789962)
IEEE Trans Med Imaging. 2024 Jan;43(1):517-528. (PMID: 37751352)
IEEE Trans Med Imaging. 2021 Sep;40(9):2415-2427. (PMID: 33945473)
Int Dent J. 2025 Feb;75(1):151-157. (PMID: 39147663)
J Dent Res. 2022 Oct;101(11):1372-1379. (PMID: 35774018)
IEEE Trans Vis Comput Graph. 2023 Aug;29(8):3617-3629. (PMID: 35404818)
J Endod. 2023 Mar;49(3):248-261.e3. (PMID: 36563779)
Otolaryngol Head Neck Surg. 2024 Jun;170(6):1492-1503. (PMID: 37595113)
IEEE J Biomed Health Inform. 2022 Jan;26(1):151-160. (PMID: 34637385)
Nature. 2024 Oct;634(8033):466-473. (PMID: 38866050)
J Dent Res. 2022 Feb;101(2):158-165. (PMID: 34416824)
Nat Commun. 2022 Jul 15;13(1):4128. (PMID: 35840566)
Sci Rep. 2022 May 7;12(1):7523. (PMID: 35525857)
Aesthet Surg J. 2023 Jul 15;43(8):930-937. (PMID: 36943815)
J Dent Educ. 2024 Sep;88(9):1257-1266. (PMID: 38715215)
J Prosthet Dent. 2024 Jun;131(6):1111-1117. (PMID: 36631366)
Int J Numer Method Biomed Eng. 2020 May;36(5):e3321. (PMID: 32043311)
Res Integr Peer Rev. 2019 Mar 26;4:5. (PMID: 30962953)
IEEE Trans Med Imaging. 2025 Feb;44(2):1083-1097. (PMID: 39365719)
J Periodontol. 2024 Jul;95(7):682-687. (PMID: 38197146)
Am J Orthod Dentofacial Orthop. 2024 May;165(5):546-555. (PMID: 38300168)
Int Endod J. 2024 Jan;57(1):108-113. (PMID: 37814369)
Dent Mater. 2023 Mar;39(3):320-332. (PMID: 36822895)
Int Dent J. 2024 Jun;74(3):616-621. (PMID: 38242810)
J Dent Res. 2022 Oct;101(11):1350-1356. (PMID: 35996332)
Oral Dis. 2024 May;30(4):1912-1918. (PMID: 37794649)
Angle Orthod. 2024 May 1;94(3):263-272. (PMID: 38195060)
J Dent Res. 2021 Apr;100(4):369-376. (PMID: 33198554)
Contributed Indexing:
Keywords: Artificial intelligence; Dentistry; Generative artificial intelligence
Entry Date(s):
Date Created: 20251119 Date Completed: 20260114 Latest Revision: 20260124
Update Code:
20260130
PubMed Central ID:
PMC12666522
DOI:
10.1016/j.identj.2025.108276
PMID:
41259905
Database:
MEDLINE

Weitere Informationen

Generative artificial intelligence (GenAI) is rapidly advancing in healthcare and is poised to transform dentistry. Given its increasing adoption in clinical and educational contexts, a comprehensive review is needed to evaluate current progress and future directions. This narrative review investigates its applications, challenges, and prospects. 74 studies from 2020 to 2025 were analyzed, covering various branches of dental medicine. GenAI has shown promise in crown design, tooth alignment, radiographic diagnosis, and educational content generation, using generative adversarial networks, diffusion models, and large language models. However, limitations remain, including insufficient clinical validation, non-standardized datasets, fragmented workflows, and ethical concerns such as data privacy and transparency. Overall, GenAI represents a transformative technology with potential to enhance diagnosis, treatment planning, and education, but continued research and standardized protocols are essential for safe integration.
(Copyright © 2025 The Authors. Published by Elsevier Inc. All rights reserved.)

Conflict of interest None disclosed.