*Result*: Mind Meets Machine: A Narrative Review of Artificial Intelligence Role in Clinical Psychology Practice.

Title:
Mind Meets Machine: A Narrative Review of Artificial Intelligence Role in Clinical Psychology Practice.
Authors:
Calderone A; IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy., Latella D; IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy., Fauci E; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Puleo R; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Sergi A; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Francesco M; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Mauro M; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Foti A; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Salemi L; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Calabrò RS; IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
Source:
Clinical psychology & psychotherapy [Clin Psychol Psychother] 2025 Nov-Dec; Vol. 32 (6), pp. e70191.
Publication Type:
Journal Article; Review
Language:
English
Journal Info:
Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9416196 Publication Model: Print Cited Medium: Internet ISSN: 1099-0879 (Electronic) Linking ISSN: 10633995 NLM ISO Abbreviation: Clin Psychol Psychother Subsets: MEDLINE
Imprint Name(s):
Original Publication: Chichester, West Sussex, England : John Wiley & Sons, c1993-
References:
Aafjes‐van Doorn, K., D. S. Spina, S. J. Horne, and V. Békés. 2024. “The Association Between Quality of Therapeutic Alliance and Treatment Outcomes in Teletherapy: A Systematic Review and Meta‐Analysis.” Clinical Psychology Review 110: 102430. https://doi.org/10.1016/j.cpr.2024.102430.
Achtyes, E. D., S. Halstead, L. Smart, et al. 2015. “Validation of Computerized Adaptive Testing in an Outpatient Nonacademic Setting: The VOCATIONS Trial.” Psychiatric Services (Washington, D.C.) 66, no. 10: 1091–1096. https://doi.org/10.1176/appi.ps.201400390.
Adler, D., D. Ben‐Zeev, V. Tseng, and T. Choudhury. 2020. “Predicting Early Warning Signs of Psychotic Relapse From Passive Sensing Data: An Approach Using Encoder‐Decoder Neural Networks (Preprint).” JMIR mHealth and uHealth 8, no. 8: e19962. https://doi.org/10.2196/19962.
Agarwal, R., M. V. Bjarnadóttir, L. Rhue, and M. Dugas. 2022. “Addressing Algorithmic Bias and the Perpetuation of Health Inequities: An AI Bias Aware Framework.” Health Policy and Technology 11: 100702. https://doi.org/10.1016/j.hlpt.2022.100702.
Alafnan, M. A. 2025. “Artificial Intelligence and Language: Bridging Arabic and English With Technology.” Journal of Ecohumanism 4, no. 1: 240–256. https://doi.org/10.62754/joe.v4i1.4961.
Al‐Kawaz, M., C. Primiani, V. Urrutia, and F. Hui. 2022. “Impact of RapidAI Mobile Application on Treatment Times in Patients With Large Vessel Occlusion.” Journal of Neurointerventional Surgery 14, no. 3: 233–236. https://doi.org/10.1136/neurintsurg‐2021‐017365.
Alowais, S. A., S. S. Alghamdi, N. Alsuhebany, et al. 2023. “Revolutionizing Healthcare: The Role of Artificial Intelligence in Clinical Practice.” BMC Medical Education 23, no. 1: 689. https://doi.org/10.1186/s12909‐023‐04698‐z.
American Psychological Association. 2017. Ethical Principles of Psychologists and Code of Conduct (2002, Amended Effective June 1, 2010, and January 1, 2017). https://www.apa.org/ethics/code.
APA Task Force on Practice of Telepsychology. 2024. APA Guidelines for the Practice of Telepsychology. American Psychological Association. https://www.apa.org/practice/guidelines/telepsychology‐revision.pdf.
Aravind, V. K., V. D. Krishnaram, and Z. Thasneem. 2012. “Boundary Crossings and Violations in Clinical Settings.” Indian Journal of Psychological Medicine 34, no. 1: 21–24. https://doi.org/10.4103/0253‐7176.96151.
Auf, H., P. Svedberg, J. Nygren, M. Nair, and L. E. Lundgren. 2025. “The Use of AI in Mental Health Services to Support Decision‐Making: Scoping Review.” Journal of Medical Internet Research 27: e63548. https://doi.org/10.2196/63548.
Ayoola, A. A., O. F. Adeoye, A. Ayoola, and A. Joy. 2025. “Telepsychiatry and Digital Mental Health Interventions: The Future of Psychiatric Nursing.” International Journal of Pharma Growth Research Review 2, no. 1: 28–38. https://doi.org/10.54660/IJPGRR.2025.2.1.28‐38.
Balcombe, L., and D. De Leo. 2022. “Evaluation of the Use of Digital Mental Health Platforms and Interventions: Scoping Review.” International Journal of Environmental Research and Public Health 20, no. 1: 362. https://doi.org/10.3390/ijerph20010362.
Benoit, J., H. Onyeaka, M. Keshavan, and J. Torous. 2020. “Systematic Review of Digital Phenotyping and Machine Learning in Psychosis Spectrum Illnesses.” Harvard Review of Psychiatry 28, no. 5: 296–304. https://doi.org/10.1097/HRP.0000000000000268.
Brenner, L. A., L. M. Betthauser, M. Penzenik, N. Bahraini, and R. D. Gibbons. 2022. “Validation of a Computerized Adaptive Test Suicide Scale (CAT‐SS) Among United States Military Veterans.” PLoS ONE 17, no. 1: e0261920. https://doi.org/10.1371/journal.pone.0261920.
Bufano, P., M. Laurino, S. Said, A. Tognetti, and D. Menicucci. 2023. “Digital Phenotyping for Monitoring Mental Disorders: Systematic Review.” Journal of Medical Internet Research 25: e46778. https://doi.org/10.2196/46778.
Cardoso, M. M. A., J. Machado‐Rugolo, L. Thabane, et al. 2024. “Application of Natural Language Processing to Predict Final Recommendation of Brazilian Health Technology Assessment Reports.” International Journal of Technology Assessment in Health Care 40, no. 1: e19. https://doi.org/10.1017/S0266462324000163.
Carini, C., and A. A. Seyhan. 2024. “Tribulations and Future Opportunities for Artificial Intelligence in Precision Medicine.” Journal of Translational Medicine 22, no. 1: 411. https://doi.org/10.1186/s12967‐024‐05067‐0.
Chin, H., H. Song, G. Baek, et al. 2023. “The Potential of Chatbots for Emotional Support and Promoting Mental Well‐Being in Different Cultures: Mixed Methods Study.” Journal of Medical Internet Research 25: e51712. https://doi.org/10.2196/51712.
Ching, T., D. S. Himmelstein, B. K. Beaulieu‐Jones, et al. 2018. “Opportunities and Obstacles for Deep Learning in Biology and Medicine.” Journal of the Royal Society, Interface 15, no. 141: 20170387. https://doi.org/10.1098/rsif.2017.0387.
Chinta, S. V., Z. Wang, A. Palikhe, et al. 2025. “AI‐Driven Healthcare: Fairness in AI Healthcare: A Survey.” PLOS Digital Health 4, no. 5: e0000864. https://doi.org/10.1371/journal.pdig.0000864.
Clark, M., and S. Bailey. 2024. Chatbots in Health Care: Connecting Patients to Information (Emerging Health Technologies). Vol. 4. Canadian Agency for Drugs and Technologies in Health. https://www.ncbi.nlm.nih.gov/books/NBK602381/.
Coghlan, S., and S. D'Alfonso. 2021. “Digital Phenotyping: An Epistemic and Methodological Analysis.” Philosophy & Technology 34, no. 4: 1905–1928. https://doi.org/10.1007/s13347‐021‐00492‐1.
Collins, G. S., K. G. M. Moons, P. Dhiman, et al. 2024. “TRIPOD+AI Statement: Updated Guidance for Reporting Clinical Prediction Models That Use Regression or Machine Learning Methods.” BMJ (Clinical Research Ed.) 385: e078378. https://doi.org/10.1136/bmj‐2023‐078378.
Conlon, D., T. Raeburn, and T. Wand. 2019. “Disclosure of Confidential Information by Mental Health Nurses, of Patients They Assess to be a Risk of Harm to Self or Others: An Integrative Review.” International Journal of Mental Health Nursing 28, no. 6: 1235–1247. https://doi.org/10.1111/inm.12642.
Da'Costa, A., J. Teke, J. Origbo, and A. Osonuga. 2025. “AI‐Driven Triage in Emergency Departments: A Review of Benefits, Challenges, and Future Directions.” International Journal of Medical Informatics 185: 105838. https://doi.org/10.1016/j.ijmedinf.2025.105838.
Dantas, J., G. Barros, A. Mutarelli, et al. 2025. “Detection of Large Vessel Occlusion Using Artificial Intelligence Tools: A Systematic Review and Meta‐Analysis.” Neuroradiology 67, no. 9: 2399–2407. https://doi.org/10.1007/s00234‐025‐03716‐9.
Dhanda, S. S., D. Panwar, C. C. Lin, et al. 2025. “Advancement in Public Health Through Machine Learning: A Narrative Review of Opportunities and Ethical Considerations.” Journal of Big Data 12: Article 154. https://doi.org/10.1186/s40537‐025‐01201‐x.
Díaz‐Rodríguez, N., J. Del Ser, M. Coeckelbergh, M. López de Prado, E. Herrera‐Viedma, and F. Herrera. 2023. “Connecting the Dots in Trustworthy Artificial Intelligence: From AI Principles, Ethics, and Key Requirements to Responsible AI Systems and Regulation.” Information Fusion 99: 101896. https://doi.org/10.1016/j.inffus.2023.101896.
Ebirim, E. C., N. M. Le, J. N. Samaha, et al. 2025. “Workflow Improvements From Automated Large Vessel Occlusion Detection Algorithms are Dependent on Care Team Engagement.” Journal of Neurointerventional Surgery: jnis‐2024‐022896. Advance Online Publication. https://doi.org/10.1136/jnis‐2024‐022896.
European Union. 2024. Artificial Intelligence Act (Regulation (EU) 2024/1689). EUR‐Lex. https://eur‐lex.europa.eu/eli/reg/2024/1689/oj/eng?utm.
Fazal, I., M. M., Bandeali, F., Shezad, & H., Gul (2025). Bridging Educational Gaps: The Role of AI and Social Media in Enhancing Access to Quality Education in Under‐Privileged Communities. Critical Review of Social Sciences Studies, 3, 2413–2431. https://doi.org/10.59075/r3dphx69.
Feng, Y., Y. Hang, W. Wu, et al. 2025. “Effectiveness of AI‐Driven Conversational Agents in Improving Mental Health Among Young People: Systematic Review and Meta‐Analysis.” Journal of Medical Internet Research 27: e69639. https://doi.org/10.2196/69639.
Figurelle, M. E., D. M. Meyer, E. S. Perrinez, et al. 2023. “Viz.ai Implementation of Stroke Augmented Intelligence and Communications Platform to Improve Indicators and Outcomes for a Comprehensive Stroke Center and Network.” AJNR. American Journal of Neuroradiology 44, no. 1: 47–53. https://doi.org/10.3174/ajnr A7716.
Fitzpatrick, K. K., A. Darcy, and M. Vierhile. 2017. “Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial.” JMIR Mental Health 4, no. 2: e19. https://doi.org/10.2196/mental.7785.
Fulmer, R., T. Davis, C. Costello, and A. Joerin. 2021. “The Ethics of Psychological Artificial Intelligence: Clinical Considerations.” Counseling and Values 66, no. 2: 131–144. https://doi.org/10.1002/cvj.12153.
Gee, D. G., K. A. DeYoung, K. A. McLaughlin, et al. 2022. “Training the Next Generation of Clinical Psychological Scientists: A Data‐Driven Call to Action.” Annual Review of Clinical Psychology 18: 43–70. https://doi.org/10.1146/annurev‐clinpsy‐081219‐092500.
Gibbons, R. D., D. J. Weiss, P. A. Pilkonis, et al. 2012. “Development of a Computerized Adaptive Test for Depression.” Archives of General Psychiatry 69, no. 11: 1104–1112. https://doi.org/10.1001/archgenpsychiatry.2012.14.
Giebel, G. D., C. Speckemeier, C. Abels, et al. 2023. “Problems and Barriers Related to the Use of Digital Health Applications: Scoping Review.” Journal of Medical Internet Research 25: e43808. https://doi.org/10.2196/43808.
Goh, Y. S., Q. R. See, N. Vongsirimas, and P. Klanin‐Yobas. 2025. “Artificial Intelligence in Diagnosing Depression Through Behavioural Cues: A Diagnostic Accuracy Systematic Review and Meta‐Analysis.” Journal of Clinical Nursing. https://doi.org/10.1111/jocn.17694 Advance online publication.
Government of Canada. 2024. Algorithmic Impact Assessment (AIA). Treasury Board of Canada Secretariat. https://open.canada.ca/data/en/dataset/5423054a‐093c‐4239‐85be‐fa0b36ae0b2e.
Graham, A. K., A. Minc, E. Staab, D. G. Beiser, R. D. Gibbons, and N. Laiteerapong. 2019. “Validation of the Computerized Adaptive Test for Mental Health in Primary Care.” Annals of Family Medicine 17, no. 1: 23–30. https://doi.org/10.1370/afm.2316.
Green, B. L., A. Murphy, and E. Robinson. 2024. “Accelerating Health Disparities Research With Artificial Intelligence.” Frontiers in Digital Health 6: 1330160. https://doi.org/10.3389/fdgth.2024.1330160.
Gutierrez, G., C. Stephenson, J. Eadie, K. Asadpour, and N. Alavi. 2024. “Examining the Role of AI Technology in Online Mental Healthcare: Opportunities, Challenges, and Implications, A Mixed‐Methods Review.” Frontiers in Psychiatry 15: 1356773. https://doi.org/10.3389/fpsyt.2024.1356773.
Hassan, M., A. Kushniruk, and E. Borycki. 2024. “Barriers to and Facilitators of Artificial Intelligence Adoption in Health Care: Scoping Review.” JMIR Human Factors 11: e48633. https://doi.org/10.2196/48633.
He, H., R. A. Raja Ghazilla, and S. H. Abdul‐Rashid. 2025. “A Systematic Review of the Usability of Telemedicine Interface Design for Older Adults.” Applied Sciences 15, no. 10: 5458. https://doi.org/10.3390/app15105458.
He, Y., L. Yang, C. Qian, et al. 2023. “Conversational Agent Interventions for Mental Health Problems: Systematic Review and Meta‐Analysis of Randomized Controlled Trials.” Journal of Medical Internet Research 25: e43862. https://doi.org/10.2196/43862.
Hickman, L., C. N. Herde, F. Lievens, and L. Tay. 2023. “Automatic Scoring of Speeded Interpersonal Assessment Center Exercises via Machine Learning: Initial Psychometric Evidence and Practical Guidelines.” International Journal of Selection and Assessment 31, no. 2: 225–239. https://doi.org/10.1111/ijsa.12418.
Hirani, R., K. Noruzi, H. Khuram, et al. 2024. “Artificial Intelligence and Healthcare: A Journey Through History, Present Innovations, and Future Possibilities.” Life (Basel, Switzerland) 14, no. 5: 557. https://doi.org/10.3390/life14050557.
Hombeck, J., H. Voigt, and K. Lawonn. 2024. “Voice User Interfaces for Effortless Navigation in Medical Virtual Reality Environments.” Computers & Graphics 124: 104069. https://doi.org/10.1016/j.cag.2024.104069.
Hoose, S., and K. Králiková. 2024. “Artificial Intelligence in Mental Health Care: Management Implications, Ethical Challenges, and Policy Considerations.” Administrative Sciences 14, no. 9: 227. https://doi.org/10.3390/admsci14090227.
Huang, Y., J. Guo, W. H. Chen, et al. 2024. “A Scoping Review of Fair Machine Learning Techniques When Using Real‐World Data.” Journal of Biomedical Informatics 151: 104622. https://doi.org/10.1016/j.jbi.2024.104622.
Hunkenschroer, A. L., and C. Luetge. 2022. “Ethics of AI‐Enabled Recruiting and Selection: A Review and Research Agenda.” Journal of Business Ethics 178: 977–1007. https://doi.org/10.1007/s10551‐022‐05049‐6.
Insel, T. R. 2017. “Digital Phenotyping: Technology for a New Science of Behavior.” JAMA 318, no. 13: 1215–1216. https://doi.org/10.1001/jama.2017.11295.
Jacob, K. S., and A. Kuruvilla. 2012. “Psychotherapy Across Cultures: The Form‐Content Dichotomy.” Clinical Psychology & Psychotherapy 19, no. 1: 91–95. https://doi.org/10.1002/cpp.736.
Jesudason, D., S. Bacchi, and T. Bastiampillai. 2025. “Artificial Intelligence (AI) in Psychotherapy: A Challenging Frontier.” Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists 33: 10398562251346075. Advance Online Publication. https://doi.org/10.1177/10398562251346075.
Kamath, J., R. Leon Barriera, N. Jain, E. Keisari, and B. Wang. 2022. “Digital Phenotyping in Depression Diagnostics: Integrating Psychiatric and Engineering Perspectives.” World Journal of Psychiatry 12, no. 3: 393–409. https://doi.org/10.5498/wjp.v12.i3.393.
Khalil, S. S., N. S. Tawfik, and M. Spruit. 2024. “Federated Learning for Privacy‐Preserving Depression Detection With Multilingual Language Models in Social Media Posts.” Patterns (New York, N.Y.) 5, no. 7: 100990. https://doi.org/10.1016/j.patter.2024.100990.
Khogali, H. O., and S. Mekid. 2023. “The Blended Future of Automation and AI: Examining Some Long‐Term Societal and Ethical Impact Features.” Technology in Society 73: 102232. https://doi.org/10.1016/j.techsoc.2023.102232.
Krishnan, G., S. Singh, M. Pathania, et al. 2023. “Artificial Intelligence in Clinical Medicine: Catalyzing a Sustainable Global Healthcare Paradigm.” Frontiers in Artificial Intelligence 6: 1227091. https://doi.org/10.3389/frai.2023.1227091.
Laymouna, M., Y. Ma, D. Lessard, T. Schuster, K. Engler, and B. Lebouché. 2024. “Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review.” Journal of Medical Internet Research 26: e56930. https://doi.org/10.2196/56930.
Lederman, R., and S. D'Alfonso. 2021. “The Digital Therapeutic Alliance: Prospects and Considerations.” JMIR mental health 8, no. 7: e31385. https://doi.org/10.2196/31385.
Lee, E. E., J. Torous, M. De Choudhury, et al. 2021. “Artificial Intelligence for Mental Health Care: Clinical Applications, Barriers, Facilitators, and Artificial Wisdom.” Biological Psychiatry. Cognitive Neuroscience and Neuroimaging 6, no. 9: 856–864. https://doi.org/10.1016/j.bpsc.2021.02.001.
Lejeune, A., A. Le Glaz, P. A. Perron, et al. 2022. “Artificial Intelligence and Suicide Prevention: A Systematic Review.” European Psychiatry: Journal of the Association of European Psychiatrists 65, no. 1: 1–22. Advance Online Publication. https://doi.org/10.1192/j.eurpsy.2022.8.
Li, H., R. Zhang, Y. C. Lee, R. E. Kraut, and D. C. Mohr. 2023. “Systematic Review and Meta‐Analysis of AI‐Based Conversational Agents for Promoting Mental Health and Well‐Being.” npj Digital Medicine 6, no. 1: 236. https://doi.org/10.1038/s41746‐023‐00979‐5.
Liu, L., L. Liu, H. A. Wafa, F. Tydeman, W. Xie, and Y. Wang. 2024. “Diagnostic Accuracy of Deep Learning Using Speech Samples in Depression: A Systematic Review and Meta‐Analysis.” Journal of the American Medical Informatics Association: JAMIA 31, no. 10: 2394–2404. https://doi.org/10.1093/jamia/ocae189.
Liu, X., S. C. Rivera, D. Moher, M. J. Calvert, A. K. Denniston, and SPIRIT‐AI and CONSORT‐AI Working Group. 2020. “Reporting Guidelines for Clinical Trial Reports for Interventions Involving Artificial Intelligence: The CONSORT‐AI Extension.” BMJ (Clinical research ed.) 370: m3164. https://doi.org/10.1136/bmj.m3164.
Longo, L., M. Brcic, F. Cabitza, et al. 2024. “Explainable Artificial Intelligence (XAI) 2.0: A Manifesto of Open Challenges and Interdisciplinary Research Directions.” Information Fusion 106: 102301. https://doi.org/10.1016/j.inffus.2024.102301.
Low, D. M., L. Rumker, T. Talkar, J. Torous, G. Cecchi, and S. S. Ghosh. 2020. “Natural Language Processing Reveals Vulnerable Mental Health Support Groups and Heightened Health Anxiety on Reddit During COVID‐19: Observational Study.” Journal of Medical Internet Research 22, no. 10: e22635. https://doi.org/10.2196/22635.
MacIntyre, M. R., R. G. Cockerill, O. F. Mirza, and J. M. Appel. 2023. “Ethical Considerations for the Use of Artificial Intelligence in Medical Decision‐Making Capacity Assessments.” Psychiatry Research 328: 115466. https://doi.org/10.1016/j.psychres.2023.115466.
Mahajan, P. 2025. The Soul of the AI: Governance, Ethics, and the Future of Human–AI Integration (ISBN 978–93–343‐2333‐7). R. C. Patel Institute of Technology. https://doi.org/10.5281/zenodo.15789678.
Maleki Varnosfaderani, S., and M. Forouzanfar. 2024. “The Role of AI in Hospitals and Clinics: Transforming Healthcare in the 21st Century.” Bioengineering (Basel, Switzerland) 11, no. 4: 337. https://doi.org/10.3390/bioengineering11040337.
Malgaroli, M., T. D. Hull, J. M. Zech, and T. Althoff. 2023. “Natural Language Processing for Mental Health Interventions: A Systematic Review and Research Framework.” Translational Psychiatry 13, no. 1: 309. https://doi.org/10.1038/s41398‐023‐02592‐2.
Malheiro, V., B. Santos, A. Figueiras, and F. Mascarenhas‐Melo. 2025. “The Potential of Artificial Intelligence in Pharmaceutical Innovation: From Drug Discovery to Clinical Trials.” Pharmaceuticals 18, no. 6: 788. https://doi.org/10.3390/ph18060788.
Malouin‐Lachance, A., J. Capolupo, C. Laplante, and A. Hudon. 2025. “Does the Digital Therapeutic Alliance Exist?” Integrative Review. JMIR Mental Health 12: e69294. https://doi.org/10.2196/69294.
Mansoor, M. A., and K. H. Ansari. 2024. “Early Detection of Mental Health Crises Through Artificial‐Intelligence‐Powered Social Media Analysis: A Prospective Observational Study.” Journal of Personalized Medicine 14, no. 9: 958. https://doi.org/10.3390/jpm14090958.
Martinez‐Gutierrez, J. C., Y. Kim, S. Salazar‐Marioni, et al. 2023. “Automated Large Vessel Occlusion Detection Software and Thrombectomy Treatment Times: A Cluster Randomized Clinical Trial.” JAMA Neurology 80, no. 11: 1182–1190. https://doi.org/10.1001/jamaneurol.2023.3206.
Mbunge, E., C. L. Jack, M. N. Sibiya, and J. Batani. 2025. “Review of Implementation Barriers and Strategic Approaches for Improving mHealth Systems Utilization in Africa: Lessons Learnt From South Africa and Kenya.” Telematics and Informatics Reports 19: 100228. https://doi.org/10.1016/j.teler.2025.100228.
McInnis, B. J., R. Pindus, D. Kareem, and C. Nebeker. 2024. “Considerations for the Design of Informed Consent in Digital Health Research: Participant Perspectives.” Journal of Empirical Research on Human Research Ethics: JERHRE 19, no. 4–5: 175–185. https://doi.org/10.1177/15562646241290078.
Mennella, C., U. Maniscalco, G. De Pietro, and M. Esposito. 2024. “Ethical and Regulatory Challenges of AI Technologies in Healthcare: A Narrative Review.” Heliyon 10, no. 4: e26297. https://doi.org/10.1016/j.heliyon.2024.e26297.
Miller, G. J. 2022. “Stakeholder Roles in Artificial Intelligence Projects.” Project Leadership and Society 3: 100068. https://doi.org/10.1016/j.plas.2022.100068.
Mitchell, M., S. Wu, A. Zaldivar, et al. 2019. Model Cards for Model Reporting. In Proceedings of the 2019 Conference on Fairness, Accountability, and Transparency (FAT’19)* (pp. 220–229). Association for Computing Machinery. https://doi.org/10.1145/3287560.3287596.
Mohr, D. C., M. Zhang, and S. M. Schueller. 2017. “Personal Sensing: Understanding Mental Health Using Ubiquitous Sensors and Machine Learning.” Annual Review of Clinical Psychology 13: 23–47. https://doi.org/10.1146/annurev‐clinpsy‐032816‐044949.
Moons, K. G. M., J. A. A. Damen, T. Kaul, et al. 2025. “PROBAST+AI: An Updated Quality, Risk of Bias, and Applicability Assessment Tool for Prediction Models Using Regression or Artificial Intelligence Methods.” BMJ (Clinical research ed.) 388: e082505. https://doi.org/10.1136/bmj‐2024‐082505.
Moshe, I., Y. Terhorst, K. Opoku Asare, et al. 2021. “Predicting Symptoms of Depression and Anxiety Using Smartphone and Wearable Data.” Frontiers in Psychiatry 12: 625247. https://doi.org/10.3389/fpsyt.2021.625247.
Naderbagi, A., V. Loblay, I. U. M. Zahed, et al. 2024. “Cultural and Contextual Adaptation of Digital Health Interventions: Narrative Review.” Journal of Medical Internet Research 26: e55130. https://doi.org/10.2196/55130.
Nakao, M., K. Shirotsuki, and N. Sugaya. 2021. “Cognitive‐Behavioral Therapy for Management of Mental Health and Stress‐Related Disorders: Recent Advances in Techniques and Technologies.” BioPsychoSocial medicine 15, no. 1: 16. https://doi.org/10.1186/s13030‐021‐00219‐w.
Nasir, S., R. A. Khan, and S. Bai. 2024. “Ethical Framework for Harnessing the Power of AI in Healthcare and Beyond.” IEEE Access 12: 45931–45945. https://doi.org/10.1109/ACCESS.2024.3369912.
Naved, B. A., and Y. Luo. 2024. “Contrasting Rule and Machine Learning Based Digital Self Triage Systems in the USA.” npj Digital Medicine 7, no. 1: 381. https://doi.org/10.1038/s41746‐024‐01367‐3.
Nepal, S., A. Pillai, W. Wang, et al. 2024. “MoodCapture: Depression Detection Using In‐the‐Wild Smartphone Images.” In Proceedings of the SIGCHI Conference on Human Factors in Computing Systems. CHI Conference, vol. 2024, 996. https://doi.org/10.1145/3613904.3642680.
Ni, Y., and F. Jia. 2025. “A Scoping Review of AI‐Driven Digital Interventions in Mental Health Care: Mapping Applications Across Screening, Support, Monitoring, Prevention, and Clinical Education.” Healthcare (Basel, Switzerland) 13, no. 10: 1205. https://doi.org/10.3390/healthcare13101205.
NIST. 2023. AI Risk Management Framework (1.0). https://nvlpubs.nist.gov/nistpubs/ai/nist.ai.100‐1.pdf?utm.
Ohm, P. 2009. “Broken Promises of Privacy: Responding to the Surprising Failure of Anonymization.” UCLA Law Review 57: 1701–1777. https://www.researchgate.net/publication/228213669_Broken_Promises_of_Privacy_Responding_to_the_Surprising_Failure_of_Anonymization.
Omboni, S., R. S. Padwal, T. Alessa, et al. 2022. “The Worldwide Impact of Telemedicine During COVID‐19: Current Evidence and Recommendations for the Future.” Connected Health 1: 7–35. https://doi.org/10.20517/ch.2021.03.
Onnela, J. P., and S. L. Rauch. 2016. “Harnessing Smartphone‐Based Digital Phenotyping to Enhance Behavioral and Mental Health.” Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 41, no. 7: 1691–1696. https://doi.org/10.1038/npp.2016.7.
Opland, C., and T. J. Torrico. 2024. “Psychodynamic Therapy.” In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK606117/.
Pal, S., M., Sundic, M., Panda, A., John, & S., Mandal (2024). Transparency in AI Systems: A Moral Imperative. https://www.researchgate.net/publication/387428727_Transparency_in_AI_Systems_A_Moral_Imperative.
Paterson, J. M. 2025. “AI Mimicking and Interpreting Humans: Legal and Ethical Reflections.” Journal of Bioethical Inquiry 22: 539–550. https://doi.org/10.1007/s11673‐025‐10424‐9. Advance Online Publication.
Pham, T. 2025. “Ethical and Legal Considerations in Healthcare AI: Innovation and Policy for Safe and Fair Use.” Royal Society Open Science 12, no. 5: 241873. https://doi.org/10.1098/rsos.241873.
Porto, B. M. 2024. “Improving Triage Performance in Emergency Departments Using Machine Learning and Natural Language Processing: A Systematic Review.” BMC Emergency Medicine 24, no. 1: 219. https://doi.org/10.1186/s12873‐024‐01135‐2.
Rasool, A., S. Aslam, N. Hussain, S. Imtiaz, and W. Riaz. 2025. “nBERT: Harnessing NLP for Emotion Recognition in Psychotherapy to Transform Mental Health Care.” Information 16, no. 4: 301. https://doi.org/10.3390/info16040301.
Razzaq, K., and M. Shah. 2025. “Machine Learning and Deep Learning Paradigms: From Techniques to Practical Applications and Research Frontiers.” Computers 14, no. 3: 93. https://doi.org/10.3390/computers14030093.
Rony, M. K. K., D. C. Das, M. T. Khatun, et al. 2025. “Artificial Intelligence in Psychiatry: A Systematic Review and Meta‐Analysis of Diagnostic and Therapeutic Efficacy.” DIGITAL HEALTH 11: 20552076251330528. https://doi.org/10.1177/20552076251330528.
Royal College of Psychiatrists. 2023. Digital Literacy Framework: Data and Digital Literacy for Psychiatrists. https://www.rcpsych.ac.uk/docs/default‐source/training/curricula‐and‐guidance/data‐and‐digital‐literacy‐for‐psychiatrists‐feb‐2023‐v1‐2.pdf?sfvrsn=bbcc8dd0_4.
Saccaro, L. F., G. Amatori, A. Cappelli, R. Mazziotti, L. Dell'Osso, and G. Rutigliano. 2021. “Portable Technologies for Digital Phenotyping of Bipolar Disorder: A Systematic Review.” Journal of Affective Disorders 295: 323–338. https://doi.org/10.1016/j.jad.2021.08.052.
Sadeghi, Z., R. Alizadehsani, M. A. Cifci, et al. 2024. “A Review of Explainable Artificial Intelligence in Healthcare.” Computers and Electrical Engineering 118, no. Part A: 109370. https://doi.org/10.1016/j.compeleceng.2024.109370.
Sauerbrei, A., A. Kerasidou, F. Lucivero, and N. Hallowell. 2023. “The Impact of Artificial Intelligence on the Person‐Centred, Doctor–Patient Relationship: Some Problems and Solutions.” BMC Medical Informatics and Decision Making 23, no. 1: 73. https://doi.org/10.1186/s12911‐023‐02162‐y.
Serrano, D. R., F. C. Luciano, B. J. Anaya, et al. 2024. “Artificial Intelligence (AI) Applications in Drug Discovery and Drug Delivery: Revolutionizing Personalized Medicine.” Pharmaceutics 16, no. 10: 1328. https://doi.org/10.3390/pharmaceutics16101328.
Seuling, P. D., J. C. Fendel, L. Spille, A. S. Göritz, and S. Schmidt. 2024. “Therapeutic Alliance in Videoconferencing Psychotherapy Compared to Psychotherapy in Person: A Systematic Review and Meta‐Analysis.” Journal of Telemedicine and Telecare 30, no. 10: 1521–1531. https://doi.org/10.1177/1357633X231161774.
Sharma, A., I. W. Lin, A. S. Miner, and D. C. Atkins. 2023. “Human–AI Collaboration Enables More Empathic Conversations in Text‐Based Peer‐to‐Peer Mental Health Support.” Nature Machine Intelligence 5, no. 1: 1–12. https://doi.org/10.1038/s42256‐022‐00593‐2.
Snell, K. I. E., L. Archer, J. Ensor, et al. 2021. “External Validation of Clinical Prediction Models: Simulation‐Based Sample Size Calculations Were More Reliable Than Rules‐of‐Thumb.” Journal of Clinical Epidemiology 135: 79–89. https://doi.org/10.1016/j.jclinepi.2021.02.011.
Soori, M., B. Arezoo, and R. Dastres. 2023. “Artificial Intelligence, Machine Learning and Deep Learning in Advanced Robotics: A Review.” Cognitive Robotics 3: 54–70. https://doi.org/10.1016/j.cogr.2023.04.001.
Spytska, L. 2025. “The Use of Artificial Intelligence in Psychotherapy: Development of Intelligent Therapeutic Systems.” BMC Psychology 13, no. 1: 175. https://doi.org/10.1186/s40359‐025‐02491‐9.
Thakkar, A., A. Gupta, and A. De Sousa. 2024. “Artificial Intelligence in Positive Mental Health: A Narrative Review.” Frontiers in Digital Health 6: 1280235. https://doi.org/10.3389/fdgth.2024.1280235.
Tippins, N., F. L. Oswald, and S. M. McPhail. 2021. “Scientific, Legal, and Ethical Concerns About AI‐Based Personnel Selection Tools: A Call to Action.” Personnel Assessment and Decisions 7, no. 2. https://doi.org/10.25035/pad.2021.02.001.
Torous, J., S. Bucci, I. H. Bell, et al. 2021. “The Growing Field of Digital Psychiatry: Current Evidence and the Future of Apps, Social Media, Chatbots, and Virtual Reality.” World Psychiatry: Official Journal of the World Psychiatric Association (WPA) 20, no. 3: 318–335. https://doi.org/10.1002/wps.20883.
Torous, J., J. Linardon, S. B. Goldberg, et al. 2025. “The Evolving Field of Digital Mental Health: Current Evidence and Implementation Issues for Smartphone Apps, Generative Artificial Intelligence, and Virtual Reality.” World Psychiatry: Official Journal of the World Psychiatric Association (WPA) 24, no. 2: 156–174. https://doi.org/10.1002/wps.21299.
Torous, J., P. Staples, I. Barnett, L. R. Sandoval, M. Keshavan, and J. P. Onnela. 2018. “Characterizing the Clinical Relevance of Digital Phenotyping Data Quality With Applications to a Cohort With Schizophrenia.” npj Digital Medicine 1: 15. https://doi.org/10.1038/s41746‐018‐0022‐8.
Tudor Car, L., D. A. Dhinagaran, B. M. Kyaw, et al. 2020. “Conversational Agents in Health Care: Scoping Review and Conceptual Analysis.” Journal of Medical Internet Research 22, no. 8: e17158. https://doi.org/10.2196/17158.
Tyler, S., M. Olis, N. Aust, et al. 2024. “Use of Artificial Intelligence in Triage in Hospital Emergency Departments: A Scoping Review.” Cureus 16, no. 5: e59906. https://doi.org/10.7759/cureus.59906.
Udahemuka, G., K. Djouani, and A. M. Kurien. 2024. “Multimodal Emotion Recognition Using Visual, Vocal and Physiological Signals: A Review.” Applied Sciences 14, no. 17: 8071. https://doi.org/10.3390/app14178071.
Ueda, D., T. Kakinuma, S. Fujita, et al. 2024. “Fairness of Artificial Intelligence in Healthcare: Review and Recommendations.” Japanese Journal of Radiology 42, no. 1: 3–15. https://doi.org/10.1007/s11604‐023‐01474‐3.
Vaidyam, A., H. Wisniewski, J. Halamka, S. Bhatia, and M. Keshavan. 2019. “Chatbots and Conversational Agents in Mental Health: A Review of the Psychiatric Landscape.” Canadian Journal of Psychiatry 64, no. 7: 456–464. https://doi.org/10.1177/0706743719828977.
Van Calster, B., D. J. McLernon, M. van Smeden, L. Wynants, and E. W. Steyerberg. 2019. “Calibration: The Achilles Heel of Predictive Analytics.” BMC Medicine 17: 230. https://doi.org/10.1186/s12916‐019‐1466‐7.
Van Orden, K., D. M. Meyer, E. S. Perrinez, et al. 2023. “(VISIION‐S): Viz.ai Implementation of Stroke Augmented Intelligence and Communications Platform to Improve Indicators and Outcomes for a Comprehensive Stroke Center and Network Sustainability.” Journal of Stroke and Cerebrovascular Diseases 32, no. 10: 107303. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107303.
Vickers, A. J., and E. B. Elkin. 2006. “Decision Curve Analysis: A Novel Method for Evaluating Prediction Models.” Medical Decision Making: An International Journal of the Society for Medical Decision Making 26, no. 6: 565–574. https://doi.org/10.1177/0272989X06295361.
Weiner, E. B., I. Dankwa‐Mullan, W. A. Nelson, and S. Hassanpour. 2025. “Ethical Challenges and Evolving Strategies in the Integration of Artificial Intelligence Into Clinical Practice.” PLOS Digital Health 4, no. 4: e0000810. https://doi.org/10.1371/journal.pdig.0000810.
Whitehead, L., J. Talevski, F. Fatehi, and A. Beauchamp. 2023. “Barriers to and Facilitators of Digital Health Among Culturally and Linguistically Diverse Populations: Qualitative Systematic Review.” Journal of Medical Internet Research 25: e42719. https://doi.org/10.2196/42719.
WHO. 2025. Ethics and Governance of AI for Health: LMM Guidance. https://www.who.int/publications/i/item/9789240084759?utm.
Xu, Y., X. Liu, X. Cao, et al. 2021. “Artificial Intelligence: A Powerful Paradigm for Scientific Research.” Innovation 2, no. 4: 100179. https://doi.org/10.1016/j.xinn.2021.100179.
Yeung, A. W. K., A. Torkamani, A. J. Butte, et al. 2023. “The Promise of Digital Healthcare Technologies.” Frontiers in Public Health 11: 1196596. https://doi.org/10.3389/fpubh.2023.1196596.
Zafar, F., L. Fakhare Alam, R. R. Vivas, et al. 2024. “The Role of Artificial Intelligence in Identifying Depression and Anxiety: A Comprehensive Literature Review.” Cureus 16, no. 3: e56472. https://doi.org/10.7759/cureus.56472.
Zhang, Y., J. Wang, H. Zong, et al. 2025. “The Comprehensive Clinical Benefits of Digital Phenotyping: From Broad Adoption to Full Impact.” npj Digital Medicine 8, no. 1: 196. https://doi.org/10.1038/s41746‐025‐01602‐5.
Zhou, W., F. Liu, H. Zheng, and R. Zhao. 2025. “Mitigating Data Bias and Ensuring Reliable Evaluation of AI Models With Shortcut Hull Learning.” Nature Communications 16, no. 1: 5513. https://doi.org/10.1038/s41467‐025‐60801‐6.
Contributed Indexing:
Keywords: artificial intelligence; clinical psychology; data privacy; digital phenotyping; ethical frameworks; machine learning; natural language processing
Entry Date(s):
Date Created: 20251205 Date Completed: 20251205 Latest Revision: 20251211
Update Code:
20260130
DOI:
10.1002/cpp.70191
PMID:
41346105
Database:
MEDLINE

*Further Information*

*Background/objectives: Clinical psychology is undergoing a profound transformation with the integration of artificial intelligence (AI) technologies. While the field has traditionally advanced from psychodynamic theories to cognitive-behavioural and evidence-based approaches, the emergence of AI presents both unprecedented opportunities and new challenges. This narrative review accordingly critically evaluates the integration of AI into clinical psychology practice, encompassing the continuum from assessment and diagnosis to intervention and follow-up care. It applies an analytic lens that differentiates clinically validated tools from experimental prototypes, and it appraises study quality against contemporary standards.
Methods: We conducted a comprehensive narrative review of the recent literature, focusing on studies and expert opinions regarding the application of machine learning (ML), deep learning (DL) and natural language processing (NLP) in psychological assessment and therapy, the use of digital phenotyping through smartphones and wearables and the implementation of AI-assisted care models in clinical practice.
Results: AI technologies are increasingly used to automate assessment scoring and analyse multimodal data, enhancing objectivity and scalability while requiring ongoing clinician oversight to address bias and interpretability issues. In therapeutic contexts, AI-driven conversational agents and hybrid 'AI-in-the-loop' systems show promise in supporting engagement and personalization, though ethical and relational concerns remain.
Conclusions: AI offers opportunities for selected assessment, monitoring and triage tasks, but evidence remains heterogeneous. Clinical integration should be incremental and evaluative, prioritizing external validation, calibration and patient-centred outcomes.
(© 2025 John Wiley & Sons Ltd.)*